- In the joke in which Stewie makes a reference to Adolf Hitler and Eva Braun dying together, it depicts the two “performing” suicide by means of drug ingestion. In reality, Hitler shot himself and ingested a pill, while Braun just ingested a pill.
- At the end of the episode Peter mentions “Next week I run for mayor of Quahog. Do I have what it takes?” No episode with this plot followed, although "It Takes a Village Idiot, and I Married One", Lois runs for Mayor.
- When LaDawn is taking Stewie to bed they pass a frame with Lois's parents although Carter's hair and mustache are already grey even though Barbara's hair is still black.
- This is the first time Meg appears in red.
- Stewie appears on the show Blind Date.
- One of the people Lois interviews for the babysitter for Stewie is Gloop from the 1967 TV show The Herculoids.
- Before Stewie locks Jeremy in the trunk, Stewie gives him his iPod so he could listen to The Strokes while he gasps for air Stewie at first calls them “The Streeks”.
- Brian and Stewie witness the infamous ipecac scene from this episode played backwards in "Yug Ylimaf".
- This is, according to the DVD commentary, the first episode of Family Guy to make a reference to The Simpsons.
- When Neil is in his "Wolverine" regalia, he is drawn without acne. Director Greg Colton tries to justify this by saying his make-up covered it up.
- The DVD commentary confirms that LaDawn is named after Liddane Sanders, the production controller of Family Guy, American Dad!, and The Cleveland Show although closed captioning and subtitles spell her name as LaDawn.
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