Stewie names his gene-altering device, or G.A.D., after actor Josh Gad.
Stewie's operation manual for G.A.D. only features him with different Chris Hemsworth haircuts.
With Brian's operation of the device, Stewie develops a hand on his head, has his arm and legs swap positions, becomes a turtle, has extremely long legs, becomes a caveman, a creature resembling Pikachu, gets his Chris Hemsworth haircut, a bottom with no torso, a torso with no bottom, a spider, Audrey II from Little Shop of Horrors, his normal self, various blobs, a pile a poop and a Gremlins-like creature.
In the short "Mailbox Madness", Cleveland receives a text that his mother Cookie Brown has died, although this is unclear if it is only a gag in the short.