Best Western International, Inc. owns the Best Western Hotels & Resorts brand, which it licenses to over 4,700 hotels worldwide.

When Mort Goldman invites the guys and their families to his wedding with Rachel in New Orleans in "The Marrying Kind", Peter and Chris become hooked on the Best Western's breakfast buffet. Upon their return to Quahog, they become unsatisfied with Lois' cooking. Thanks to a room key card that Chris managed to keep, they sneak into the Best Western in Quahog to take advantage of of the buffet there.

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