- The title refers to the phrase 'Man's best friend.'
- Elizabeth Shoe is a pun on actress Elisabeth Shue.
- After wrecking Joe's car, Peter makes a reference to Caitlyn Jenner's car crash that killed a 70 year-old woman.[1]
Previous Episode's References /// Boy's Best Friend's References \\\ Next Episode's References
| << Season 18 | Family Guy Season 19 | Season 20 >> | ||||||
| #01 | Stewie's First Word | #08 | Pawtucket Pat | #15 | Customer of the Week | |||
| #02 | The Talented Mr. Stewie | #09 | The First No L | #16 | Who's Brian Now? | |||
| #03 | Boys & Squirrels | #10 | Fecal Matters | #17 | Young Parent Trap | |||
| #04 | Cutawayland | #11 | Boy's Best Friend | #18 | Meg Goes to College | |||
| #05 | La Famiglia Guy | #12 | And Then There's Fraud | #19 | Family Cat | |||
| #06 | Meg's Wedding | #13 | PeTerminator | #20 | Tales of Former Sports Glory | |||
| #07 | Wild Wild West | #14 | The Marrying Kind | |||||