- This episode is a complete break from the traditional Family Guy formula as there are no cutaway gags, flashbacks or music used whatsoever.
- The episode is touted as the 150th episode but the count includes dividing up Blue Harvest into two parts, Similarly dividing Something, Something Something Dark Side that isn't set to air until the following week but was in production first and including Partial Terms of Endearment which will be a DVD release in the future but was also in production earlier. The broadcast episode count does not take in these considerations.
- Brian mentions the fact that Stewie can invent a time machine, which he did twice, once in Mind Over Murder and once in Road to Germany.
- Except in archive footage, Peter, Lois, and Meg do not appear. Chris does not appear at all.
- Brian says that he voted for John McCain in the presidential election.
- Stewie claims that there was a sneak peek at the movie Toy Story 3 in Micheal Jackson's last recording for this show.
Syndicated edits
The syndicated and iTunes version of this episode is heavily edited:
- The opening scene of Brian and Stewie introducing the episode as well as the musical numbers montage is edited out.
- The theme song is also edited and instead the words "Family Guy" is shown at the beginning of the episode just like in Brian Griffin's House of Payne.
- Stewie's line, "That's science, Brian, I'm not Houdini." is cut.
- Stewie's suggestion for Brian to lick his ass is cut as well as the licking of Stewie's ass being cut.
- Stewie's call to Wyndham's ends much sooner than the aired version.
- Some of Stewie's dialogue before Brian says, "I voted for McCain is edited out."
- The security camera is not in this version of the episode.
- Stewie does not mention his time in yoga class.
- Brian does not say he doesn't like strawberry yogurt and Stewie does not mention how he eats the same thing every day out of a bowl.
- Some of the dialogue about why Brian has a gun are edited out.
- In the end, the credits roll in complete silence.
Previous Episode's Notes/Trivia /// Brian & Stewie's Notes/Trivia \\\ Next Episode's Notes/Trivia