Conan Christopher O'Brien (born April 18, 1963) is an American television host, comedian, writer, producer, and voice actor. He is best known for hosting several late-night talk shows, the most recent of which, Conan, premiered on American cable television station TBS in 2010.
Conan appears as himself in "In Harmony's Way" when Peter Griffin and Quagmire perform as a singing duet on his show Conan. When Peter ruins the act and Quagmire walks out, Peter tries to strike up a conversation with Conan, noting that his make-up lady was crying backstage. Conan snaps at him that Peter is not to talk to him during his time.
Peter suggests watching Conan on a high-numbered television channel to Brian in "Roasted Guy".
In "Island Adventure", Stewie and Brian try to catch up a group of castaways on things they have missed out since being lost for up to twenty years.