E! Entertainment Television, or more simply referred to as E!, is an American cable television and direct broadcast satellite network. The network has been wholly owned by Comcast since November 2006.
In "The Courtship of Stewie's Father", Cleveland Brown revealed he once worked for E!. A cutaway shows him working at an awards show, covering it for the network, calling over Penelope Cruz, who he mistook for Seabiscuit. After Cruz clarifies she is not a horse, he feeds her a carrot.
Pearl Burton was the subject of an episode of E! Mysteries & Scandals, hosted by A. J. Benzer in "Brian Wallows and Peter's Swallows". The episode helped Brian Griffin delve into Burton's reasons for isolation and bitterness.
Andrea Fay Friedman, the voice of Ellen in "Extra Large Medium", was the final person featured on Born Different 2: More Amazing Stories in 2011. Her role was mentioned, and was packaged with a clip from the episode, specifically the character's date with Chris Griffin.