Feast of San Gennaro, also known as the Feast of St Januarius is a holiday celebrated on September 19th on the Catholic calendar to celebrate Saint Januarius, the Patron Saint of Naples.
The Griffins attend a street festival to celebrate the feast in "Bookie of the Year", where Peter is enlisted to try to introduce an elderly Italian lady to a computer tablet, pursues snow cones and is amazed at a blue one, as Chris smashes an arcade game in a fit of rage.
Meanwhile, Brian and Stewie bump into Frank Sinatra, Jr. while in search of Italian food and he convinces them to open a restaurant with him.
During the Feast in "Stand By Meg", Principal Shepherd walks though the festival on the way to his apartment, unaware that Chris is waiting to ambush him.
In a parody of Rocky in "Tales of Former Sports Glory", Peter invites Lois to the Festival of San Gennaro held the previous week.