- The press release credited Kevin Michael Richardson as the giant chicken, although he actually provided the voice of the giant cock.[1]
- Although Peter simply refers to him as the giant chicken, the giant cock uses Ernie's established name.
- Ernie's now ex-wife, Nicole, makes her third appearance.
- This episode only has a single cutaway gag.
- This is the second time that a dog character is joked to be part cat. The first time was in "Life of Brian" when Vinny answers Peter's question on what breed he is and he claims to be a 'Pussy Hound'.
- Meg reveals that Peter suffers from Hemophobia, a fear of the sight blood.
- Peter also reveals that he suffers from Trypanophobia, fear of needles.
- Peter breaks the Fourth wall by mentioning the voice actor of Ernie the giant chicken.
- Despite it being hinted in New Kidney in Town that he created him, Dr. Hartman makes no mention of this in front of Ernie and Peter.
- Meg's high speed run is set to "Ode To My Family" by The Cranberries.[2]
- Peter uses Shazam to confirm that Paula Cole's "Where Have All the Cowboys Gone?" plays at the grocery store.[3]
- When applying Cardioversion to the first patient, Peter calls for C+C Music Factory's "Gonna Make You Sweat (Everybody Dance Now)".
- During the second patient, he hints at Chumbawamba's "Tubthumping".
- "Sail" by AWOLNATION plays when Brian jumps off the roof.
- When talking with Quagmire, Peter confuses HIPAA with a hippopotamus.
- Dr. Hartman tells Peter that if he refused to work on anybody he hated, they'd all die. He instead works out his frustrations doing an angry dance from Footloose.
- Peter is incapable of being happy after doing too much ecstasy in his 20s.
- Peter and Ernie both thought they'd get to eat the other for Thanksgiving.
- Chris plays 'footsie' with Lois under the table.
- Although the kids are unaware of the ongoing feud between Peter and Ernie, they all perk up when he compares it to the battle of wits between Bart Simpson and Sideshow Bob of The Simpsons.
- The clip of John Candy comes from Planes, Trains and Automobiles.
- Stewie's analysis of Brian comes up to 95%.
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| << Season 18 | Family Guy Season 19 | Season 20 >> | ||||||
| #01 | Stewie's First Word | #08 | Pawtucket Pat | #15 | Customer of the Week | |||
| #02 | The Talented Mr. Stewie | #09 | The First No L | #16 | Who's Brian Now? | |||
| #03 | Boys & Squirrels | #10 | Fecal Matters | #17 | Young Parent Trap | |||
| #04 | Cutawayland | #11 | Boy's Best Friend | #18 | Meg Goes to College | |||
| #05 | La Famiglia Guy | #12 | And Then There's Fraud | #19 | Family Cat | |||
| #06 | Meg's Wedding | #13 | PeTerminator | #20 | Tales of Former Sports Glory | |||
| #07 | Wild Wild West | #14 | The Marrying Kind | |||||