Jennifer Ann "Jenny" McCarthy (born November 1, 1972) is an American model, comedienne, actress, author, and activist. She began her career as a Playboy magazine model in 1993, before launching a television and film acting career. Most recently, she has written books about parenting, and has become an activist promoting claims that vaccines cause autism' and that chelation therapy is effective against autism, indirectly leading many children to become gravely ill.
She was used in a hypothetical sex situation by Quagmire in "Believe It or Not, Joe's Walking on Air".
She appears in a photo shot with boyfriend Jim Carrey when Stewie compares Meg and Luke to when a crazy girl hooks up with an even crazier guy in "Dial Meg for Murder".
Peter tries to use Jenny McCarthy in a debate over childhood vaccinations as a selling point for American to Mahmoud in "Turban Cowboy". He also uses her in discussing vaccinations with Brian in "Hot Shots".