Mort Goldman is Neil Goldman's father and the husband of Muriel Goldman. He is noticeably Jewish and owns Goldman's Pharmacy. He once bowled a perfect game in a rather unorthodox way by rolling the ball extremely slowly down the lane. Mort is given to conversations about rather depressing, and often grotesque, topics. Mort doesn't mind revealing details about his customer's personal health problems, for example he once went into the details about a man with hemorrhoids, telling the man's daughter and her classroom that they were like stinking little balloons and that they stung him so bad that he had to apply the lotion in his car with a sock. Mort takes on the characteristics of Sol Rosenberg, a character of The Jerky Boys created by Johnny Brennan in the late 1980's.
- In the episode Mr. Saturday Knight, Mort joined the renaissance fair in an attempt to overcome his fear of swords. He tells Peter that he was stabbed in the ear by a man in a pirate suit when he was five years old, and again when he was 30. He also yelled out that he miscarried.
- Lois has her photo shoot pictures developed at Mort's pharmacy in Model Misbehavior, and then poses for a series of fliers to advertise the pharmacy. It is also shown that Mort hates the Greased-up Deaf Guy.
- In Brian the Bachelor, to ensure that Lois could not purchase acne medication to clear up his zit, Doug, Chris broke into Goldman's Pharmacy and destroyed all the acne medication.
- In Long John Peter, his pharmacy was damaged by Peter and his pirate crew, who made sure that the rack of cheap pharmacy toys was blasted.
- It is seen in Stuck Together, Torn Apart that Mort watches movies to Hotel California and that his niece is Jennifer Love Hewitt.
- In the episode No Meals on Wheels he is afraid of Peter's "scarejew" made in the likeness of Adolf Hitler and exclaims "Save Jon Stewart! He's our most important Jew!"
- In April in Quahog Mort is flipped off by Jesus and Jesus said "Have fun where you're going!"
- Mort also played Lando Calrissian in Something, Something, Something, Dark Side, becoming dark-skinned. He will reprise this role in It's A Trap!.