- This episode is dedicated to Carrie Fisher.
- Brian doesn't have any lines in this episode.
- Quagmire's friends come to doubt his skills as a pilot after seeing the autopilot. A deleted scene intended for "Pilling Them Softly" originally had Quagmire's motivation for taking up cooking was due to the use of autopilot.
- Peter breaks the Fourth wall and calls on the animators twice to alter the scene. Once to fix his eye, and then to change the guys into X-Men characters.
- Lois mentions that she and the other girls had a planned trip to Donna's sister's timeshare planned. Donna has a sister named Janet from The Cleveland Show.
- Melissa Etheridge's "Come To My Window" plays during the guy's trip to San Francisco.
- The kid in the treehouse is seen reading a MAD magazine.
- The military jets that intercept and try to shoot the plane down are stylized after McDonnell Douglas F/A-18C Hornets.
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