Peter's Sperm Donation Offspring are the result of his trying to raise money for dial-up modem impression lessons in "A House Full of Peters".
Katie is one of the first to greet him after he agrees to give his consent at the sperm bank for any offspring to meet him, leading a troop of other descendants. Katie is voiced by Rachael MacFarlane.
Larry finds some mutual attraction with Lois, who notes that he looks like Peter did at the time they were married. However, Peter catches him trying to unsnap her bra and starts a fight. But as Larry nearly has the upper hand, he is knocked cold by Lois who realizes that Peter is the only one for her.
Other offspring include Tyler, a dwarf who dies because Peter forgot to feed him as he would a pet and several who identify themselves as variations of Peter, including a Chinese and German Peter.