- This episode marks the death and last appearance of Horace, meaning Horace will not appear from the show anymore.
- A drunken Peter recounts several of the Simpsons adventures such as Maggie's first word, Mr. Plow and Bart jumping the canyon as his greatest moments in life.
- This is the second appearance for Jerome after "Jerome Is the New Black".
- "I Will Remember You" by Sarah Mclachlan plays during the video tribute to Horace.
- During Peter's 80s flashback, "Only You" by Yazoo plays.
- Meg hints at having had or at least participated in an abortion or miscarriage when she tells the funeral director that she wasn't used to seeing large corpses and not floating in the toilet.
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| << Season 10 | Family Guy Season 11 | Season 12 >> | |||||||||
| #01 | Into Fat Air | #09 | Space Cadet | #17 | Bigfat | ||||||
| #02 | Ratings Guy | #10 | Brian's Play | #18 | Total Recall | ||||||
| #03 | The Old Man and the Big 'C' | #11 | The Giggity Wife | #19 | Save the Clam | ||||||
| #04 | Yug Ylimaf | #12 | Valentine's Day in Quahog | #20 | Farmer Guy | ||||||
| #05 | Joe's Revenge | #13 | Chris Cross | #21 | Roads to Vegas | ||||||
| #06 | Lois Comes Out of Her Shell | #14 | Call Girl | #22 | No Country Club for Old Men | ||||||
| #07 | Friends Without Benefits | #15 | Turban Cowboy | ||||||||
| #08 | Jesus, Mary & Joseph | #16 | 12 and a Half Angry Men | ||||||||
| 200 Episodes Later | |||||||||||