Seabreeze is the prize-winning dog of Lois' parents, the Pewterschmidts. In "Screwed the Pooch", Brian rushes onto a dog track while Seabreeze is racing and "violates" her. According to Tricia Takanawa, who did a news story on Seabreeze, it turns out that she's the heir to the Pewterschmidt fortune. She later gives birth to puppies, who are not Brian's, but Ted Turner's. Afterwards, Carter called her a whore and stomped out.
In "Valentine's Day in Quahog", Stewie gathers scores of Brian’s former girlfriends including Seabreeze to get to the bottom of why he’s unsuccessful in love.